Hexokinase Vs Glucokinase - Importance and Clinical Significance

Few points to be noted which is missing in the video content:
Glucokinase is induced by insulin while hexokinase is not
Hexokinase is feedback inhibited by glucose 6 phosphate while Glucokinase is not.

Why do we need two enzymes to catalyze the same reaction in the conversion of glucose to glucose 6 phosphate? glucokinase vs hexokinase comparison is one of the concept that most biochemistry students will be searching for and trying to understand why there is a need of two enzymes to catalyze the same reaction. This video explains all details on glucokinase and hexokinase comparison that is optimum and necessary know information for biochemistry students. Glucokinase and hexokinase enzymes are compared for their km, vmax and their affinity for glucose, their importance, and also what happens to blood glucose levels if there is a mutation in the enzyme.

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Видео Hexokinase Vs Glucokinase - Importance and Clinical Significance канала Dr.Mungli