MORPHOLOGY OF CELL INJURY: REVERSIBLE & IRREVERSIBLE. Necrosis & its types.

A series of video tutorials discussing the pathology of cell injury and adaptations.
In this tutorial , i have discussed Morphology of Reversible and Reversible cell injury
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Morphology of reversible cell injury : hydropic change
Morphology of irreversible cell injury : Autolysis,
Necrosis, types & examples

Autolysis
• “self digestion”
• Disintegration of the cell by its own hydrolytic enzymes liberated from lysosomes
• Rate of autolysis depends on the hydrolytic enzymes
• Morphology – homogenous and eosinophilic cytoplasm with loss of cellular details
Necrosis
• Localised area of cell death followed by degradation of the tissue by the hydrolytic enzymes
• ALWAYS accompanied by inflammatory reaction
Mechanisms
1. Denaturation of the intracellular proteins
2. Enzymatic digestion of the cell
Types of necrosis
• Mass of necrosis has several morphological patterns
• Coagulative
• Liquefaction
• Caseous
• Fat &
• Fibrinoid

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Please watch: "WARBURG EFFECT: Hallmark of CANCER. What, Why & How?"
https://www.youtube.com/watch?v=LXaO59IqQm8
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Видео MORPHOLOGY OF CELL INJURY: REVERSIBLE & IRREVERSIBLE. Necrosis & its types. канала ilovepathology