CHAPTER 14 - Overview of Metabolism and Metabolic Fuels

HARPER BIOCHEMISTRY
CHAPTER 14

This explains the complex metabolic processes within the human body, detailing how chemical compounds are interconverted for energy and synthesis. It differentiates between anabolic pathways, which build complex molecules, and catabolic pathways, which break them down, highlighting the role of amphibolic pathways at metabolic junctions, also discusses how different organs handle metabolic fuels in both fed and fasting states, the importance of substrate transport and enzymatic regulation for maintaining metabolic homeostasis, and the clinical implications of metabolic dysfunction, such as in diabetes and starvation. Finally, it touches upon how dietary components are interconverted and the subcellular locations of key metabolic reactions.

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