CHAPTER 13 - Disorders of Blood, Lymph, and Thymus

ROBBINS PATHOLOGY
CHAPTER 13

This provides an overview of diseases affecting white blood cells, lymph nodes, spleen, and thymus. It begins by explaining the origins and normal development of hematopoietic cells, the source of blood components. The source then details disorders of white cells, including decreases (leukopenia) and increases (leukocytosis) in number, as well as reactive proliferations. A significant portion focuses on neoplastic proliferations of white cells, broadly classifying them into lymphoid neoplasms, myeloid neoplasms, and histiocytoses, and exploring the genetic and viral factors involved in their development. Finally, the text briefly discusses diseases of the spleen and thymus, highlighting their roles in immune function and common pathological conditions like splenomegaly and thymoma.

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