Boost This Hormone & Fasting Will Be Easier

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DR. MINDY'S NOTES:

OXYTOCIN -discovered in 1906

Originally thought to be a hormone associated with social bonding, reproduction, parturition, lactation and appetite regulation.

1963 - Metabolic Effect of oxytocin started to be studied

-oxytocin enhances glucose uptake and lipid utilization in adipose tissue and skeletal muscle
-dysfunction of the oxytocin system could underlie the pathogenesis of insulin resistance and dyslipidaemia.

-ANIMAL STUDY….revealed that deficiencies in oxytocin signalling and oxytocin receptor expression lead to obesity despite normal food intake, motor activity and increased leptin levels.”

-HUMAN STUDY….Plasma oxytocin concentration is notably lower in obese individuals with diabetes, which may suggest an involvement of the oxytocin system in the pathogenesis of cardiometabolic disease”

-”More recently, small scale studies demonstrated that intranasal administration of oxytocin was associated with significant weight loss as well as improvements in insulin sensitivity and pancreatic β‐cell responsivity in human subjects.”

Where is oxytocin made?
-hypothalamus/ pituitary

Where is oxytocin metabolized?
-liver
-kidneys

What are receptor sites found for oxytocin?
-skeletal muscle
-adipose tissue
-liver
-pancreas

HOW CAN OXYTOCIN HELP YOU WITH FASTING & INSULIN RESISTANCE

1. Improves glucose uptake & insulin sensitivity

2. Induces lipolysis- Breakdown of fat

3.Down regulates the HPA axis
-reduces cortisol levels

4. Suppresses appetite
-Oxytocin markedly reduced hunger-driven food intake in the fasted state in obese men

HOW TO BE AN OXYTOCIN MASTER?

1. 8 hugs-10seconds
2. Use Love word
3. Pet a dog
4. Rollercoaster ride/skydiving -200% oxytocin spike
5. Warm & Cold Baths
6. Meditation
7. Give a gift to someone
8. Yoga
9. Music
10. Spend time with friends
11. Massage
12. Sex
13. Do something nice for someone
14. Volunteer
15. Breathwork

STUDIES:

Oxytocin in metabolic homeostasis: implications for obesity and diabetes management
https://onlinelibrary.wiley.com/doi/full/10.1111/obr.12757

The effects of oxytocin on eating behaviour and metabolism in humans
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868755

Self-soothing behaviors with particular reference to oxytocin release induced by non-noxious sensory stimulation
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290532/
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#fastingandhormones
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Видео Boost This Hormone & Fasting Will Be Easier канала Dr. Mindy Pelz