Immunology Advance: Blocking Alarmins to Treat Long-Term Disease

NIAID research fellow Kevin Vannella, Ph.D., describes results from a mouse study showing how simultaneously blocking three signaling proteins may help treat asthma and liver disease.

Reference: Vannella KM, Ramalingam TR, Borthwick LA, Barron L, Hart KM, Thompson RW, Kindrachuk KN, Cheever AW, White S, Budelsky AL, Comeau MR, Smith DE, Wynn TA. Combinatorial targeting of TSLP, IL-25, and IL-33 in type 2 cytokine-driven inflammation and fibrosis. Sci Transl Med DOI: 10.1126/scitranslmed.aaf1938 (2016)

Видео Immunology Advance: Blocking Alarmins to Treat Long-Term Disease канала NIAID