Why Zinc is VERY Important for Women (Specifically)

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Why Zinc is VERY Important for Women (Specifically)- Thomas DeLauer

Thyroid

The structure of thyroid hormone receptors contains zinc ions, crucial for the functional properties of the protein

https://www.ncbi.nlm.nih.gov/pubmed/30982439
https://www.ncbi.nlm.nih.gov/pubmed/8157857

PCOS (insulin)

Zinc & Insulin

Zinc ions can bind to insulin receptors and activate insulin signaling pathways - helps stimulate glucose uptake into cells

Believed that zinc ions inhibit glycogen synthase kinase-3beta (GSK-3beta), serine/threonine protein kinase linked with insulin resistance and type 2 diabetes (similar to what Nick mentioned in regards to Lithium)

https://www.ncbi.nlm.nih.gov/pubmed/12083774

Study - Experimental and Clinical Endocrinology & Diabetes
Study was conducted among 52 women diagnosed with PCOS and aged 18-40 years old.

Participants were randomly divided into 2 groups to receive 220 mg zinc sulfate (containing 50 mg zinc) supplements (26 people) or placebo (26 people) per day for 8 weeks

After 8 weeks of intervention, subjects who received zinc supplements had significantly increased serum zinc levels (+15.6 vs. -4.1 mg/dL, on average) compared with placebo

In addition, zinc-supplemented patients had reduced:

fasting plasma glucose (FPG) (-4.3 vs. +0.5 mg/dL)
serum insulin levels (-3.0 vs. +1.5 µIU/mL),
homeostasis model of assessment-insulin resistance (HOMA-IR) (-0.8 vs. +0.3)
homeostatic model assessment-Beta cell function (HOMA-B) (-10.6 vs. +4.9)
and increased quantitative insulin sensitivity check index (QUICKI) (+0.02 vs. -0.004) compared with placebo

Additionally, a significant reduction in serum triglycerides (-15.6 vs. +14.5 mg/dL) and VLDL-cholesterol concentrations (-3.2 vs. +2.9 mg/dL) was observed following the administration of zinc supplements compared with placebo.

https://www.ncbi.nlm.nih.gov/pubmed/25868059

Pregnancy

Low blood zinc levels are associated with pregnancy complications

Study - JAMA

One study in part Another study in pregnant women (with low blood zinc levels) found that zinc supplementation (25 mg/day) during the second half of pregnancy significantly increased infant birth weights and head circumferences

In all women, infants in the zinc supplement group had a significantly greater birth weight (126 g) and head circumference (0.4 cm) than infants in the placebo group. In women with a body mass index less than 26 kg/m2, zinc supplementation was associated with a 248-g higher infant birth weight and a 0.7-cm larger infant head circumference

https://www.ncbi.nlm.nih.gov/pubmed/7629954

Menstrual Pain

Published in the journal Medical Hypotheses, researchers gave 56 young women with dysmenorrhea zinc supplements for two menstrual cycles

Significant reductions in pain decreased by 50% during the second cycle, but not the first - suggests zinc is more effective when taken for longer periods of time

https://www.ncbi.nlm.nih.gov/pubmed/17289285

Bonus: Skin

To some extent, zinc does play a role in protecting the skin as it lessens the formation of free radicals and protects skin’s lipids (fats) and fibroblasts, the cells that make collagen, aka your skin’s support structure

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120804/

Видео Why Zinc is VERY Important for Women (Specifically) канала Thomas DeLauer