The science behind UCLA stem cell center’s clinical trial for metastatic sarcoma

Dr. Theodore Scott Nowicki and Dr. Antoni Ribas, two members of the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, are overseeing a phase I clinical trial of a novel treatment for advanced sarcomas and other cancers with a specific tumor marker called NY-ESO-1. The trial is currently recruiting and will test a therapeutic approach that genetically engineers each patient’s own blood-forming stem cells to produce cancer-fighting immune cells called T cells. The cells used in the treatment will be modified to target NY-ESO-1, a protein that is highly produced by tumor cells of many cancers including melanoma and sarcoma. Sarcomas account for one percent of all adult cancers and 15 percent of all pediatric cancers diagnosed annually in the United States.

Видео The science behind UCLA stem cell center’s clinical trial for metastatic sarcoma канала UCLA Broad Stem Cell Research Center