Intermittent Fasting Does Not Reduce Belly Fat | Intermittent Fasting & Weight Loss

Visceral Fat goes into preservation mode making it resistant to fat burning
Repeated bouts of fasting made visceral fasting more resistant over time.
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TIMELINE:

00:00 Does intermittent fasting burn stubborn belly fat?
02:40 Intermittent fasting has no significant weight loss benefit
06:36 IF=ntermittent fasting didn’t reduce belly fat in mice
08:00 Fasting too long with no variation can have an adverse effect on weight loss
08:45 Varying your fasts matters greatly for weight loss

NOTES:

Title: IF didn’t reduce belly fat in mice

Visceral Fat goes into preservation mode making it resistant to fat burning
Repeated bouts of fasting made visceral fasting more resistant over time.

What do these two studies teach us?
1. Fasting too long with no variation can have an adverse effect on weight loss
2. Varying your fasts matters greatly for weight loss

Studies:

Proteomics analysis of adipose depots after intermittent fasting reveals visceral fat preservation mechanisms

"Summary
Intermittent fasting is a beneficial dietary treatment for obesity. But the response of each distinct adipose depot is currently poorly defined. Here we explore the response of key adipose depots to every-other-day fasting (EODF) in mice using proteomics. A key change in subcutaneous white adipose tissue (scWAT) and visceral WAT (vWAT) depots is an increase in mitochondrial protein content after EODF. This effect is correlated with increased fatty acid synthesis enzymes in both WAT depots but not in brown adipose tissue. Strikingly, EODF treatment downregulates lipolysis specifically in vWAT, mediated by a large decrease in the abundance of the catecholamine receptor (ADRB3). Together, these changes are important for preservation of the visceral lipid store during EODF. Enrichment analysis highlights downregulation of inflammatory collagen IV specifically in vWAT, allowing improved insulin sensitivity. This resource for adipose-depot-specific fasting adaptations in mice is available using a web-based interactive visualization."
LINK: https://www.cell.com/cell-reports/fulltext/S2211-1247(21)00118-2

Effects of Time-Restricted Eating on Weight Loss and Other Metabolic Parameters in Women and Men With Overweight and Obesity

"Conclusions and Relevance Time-restricted eating, in the absence of other interventions, is not more effective in weight loss than eating throughout the day."
LINK: https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2771095

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Видео Intermittent Fasting Does Not Reduce Belly Fat | Intermittent Fasting & Weight Loss канала Dr. Mindy Pelz