Myasthenia Gravis | Pathophysiology, Signs & Symptoms, Diagnosis, Treatment

Myasthenia Gravis | Pathophysiology, Signs & Symptoms, Diagnosis, Treatment

Myasthenia Gravis is an autoimmune condition involving the production of autoantibodies against particular parts of the muscle and neuromuscular junction, leading to subsequent muscle weakness and fatigue. Myasthenia Gravis can lead to weakness and fatigue of particular muscle groups including the eyes, extremities and bulbar muscles. Myasthenia Gravis is diagnosed by bloodwork looking for autoantibodies (including anti-acetylcholine receptor antibody) and via imaging looking for thymomas in some cases. Myasthenia Gravis is treated with a variety of medications, including anticholinesterase inhibitors and with surgery in the case of a thymoma.

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