5 Shocking Ways You Could be Damaging Your Kidneys

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5 Shocking Ways You Could be Damaging Your Kidneys - Thomas DeLauer

Sitting Still

Published in the American Journal of Kidney Diseases who sit for long periods of time, for instance at the office from 9 to 5 every day, can improve their health, particularly their kidney function, if they take part in traditional moderate-to-vigorous intensity physical activity

More than 5,650 participants (ages 40 to 75) were analyzed for the final results, and put into groups based on two factors: how long they spent sitting each day and the amount of time they spent exercising.

After controlling for certain lifestyle factors, the risk of developing chronic kidney disease (CKD) was decreased by more than 30% in females who reported fewer than 3 hours of sitting time, compared to those who reported over 8 hours.

Males who reported fewer than 3 hours of sitting down saw a reduction of 15%. Men who were physically active for at least 30 minutes each day, reduced the risk of developing CKD by at least 30%.

https://www.ncbi.nlm.nih.gov/pubmed/22717340

https://www.health.harvard.edu/diseases-and-conditions/when-the-blood-supply-to-the-kidneys-suffers

Dehydration

Water helps remove wastes from your blood in the form of urine. Water also helps keep your blood vessels open so that blood with important nutrients can travel freely to your kidneys.

But if you become dehydrated, then it’s harder for this delivery system to work - dehydration can cause a build-up of wastes and acids in the body, and it can clog the kidneys

https://www.karger.com/Article/FullText/381239

Not Going to the Bathroom Frequently Enough

If you often resist the urge to pee, the urine remains in your bladder for a longer period, and bacteria begin multiplying much faster

https://www.ncbi.nlm.nih.gov/pubmed/29229166

Lack of Sleep

Your sleep/wake cycles regulate and coordinate your kidney function, and this organ’s tissues are renewed only when you’re sleeping

In a prospective cohort study of 4,238 participants from the Nurses’ Health Study, participants with a short sleep duration (5 hours or less) were shown to be 79% more likely to develop rapid decline in renal function (a decrease in eGFR ≥ 30%) in comparison with participants reporting a sleep duration of 7 hours

Mechanism(s)

Sleep disturbances, such as habitual sleep restriction, may predispose to incident CKD by increasing the risk of developing established CKD risk factors

As an example, individuals who report sleeping 5 or fewer hours per night are 20% more likely to develop hypertension and 57% more likely to develop incident diabetes - both of which contribute to kidney dysfunction

This internal rhythm appears to be caused by the expression of the well-known circadian rhythm master gene BMAL1

Excretion increases in the early dark hours, which lowers fluid levels and likely contributes to the dip in blood pressure that most people experience at night

However, the kidneys slow their production of urine as the night goes on, to allow us to sleep uninterrupted

*Lack of sleep disrupts this lowering of blood pressure*

https://link.springer.com/article/10.1007/PL00012172

Artificial Sweeteners (Aspartame)

In a review published in the Clinical Journal of the American Society of Nephrology, researchers looked at the role of artificial sweeteners on kidney function and found that there was an increase in kidney function decline with intake of just two diet sodas per day

This study identified 3318 women participating in the Nurses' Health Study with data on soda intake and albuminuria (a sign of kidney disease)

Consumption of ≥2 servings per day of artificially sweetened (diet) soda was independently associated with eGFR decline ≥30%

*eGFR is short for estimated glomerular filtration rate. Your eGFR is a number based on your blood test for creatinine, a waste product in your blood. It tells how well your kidneys are working*

Concluded that consumption of ≥2 servings per day of artificially sweetened soda is associated with a 2-fold increased odds for kidney function decline in women

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022238/

Aspartame

Once ingested, aspartame is metabolized to aspartic acid, phenylalanine, and methanol in the ratio of 50:40:10, respectively, and also a small amount of aspartyl phenylalanine diketopiperazine, especially during its heating

Methanol further oxidized to formaldehyde, which is accompanied by the formation of superoxide anion and hydrogen peroxide in the kidney and other organs like liver and brain

The other metabolite, diketopiperazine, seems to be a carcinogen

https://www.ncbi.nlm.nih.gov/pubmed/29038387

Cordyceps & the Kidneys

https://www.ncbi.nlm.nih.gov/pubmed/30689560
https://www.hindawi.com/journals/omcl/2019/7850863/

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