Virology Lectures 2016 #13: Intrinsic and Innate Defenses

In this and the next lecture, we discuss the myriad defenses on and in a animal host that are engaged upon encounters with viruses. If a virus gets past the chemical and physical defenses of the host, next in its way stands intrinsic defenses (always present in the cell), and then innate defenses (which must be induced by infection). Both are highly effective antiviral systems, but are antagonized by many different viral proteins - and this is one reason why viruses are successful at being maintained in populations.

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