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Virology Live #7: Transcription and RNA processing

When DNA viral genomes enter the cell, mRNAs must be made before DNA replication can occur. This step, called transcription, can only occur on double-stranded templates. The enzyme that carries out transcription, DNA dependent RNA polymerase, may be encoded by the cell or by the viral genome. In this session we discuss regulation of transcription, positive feedback loops and transcriptional cascades and how these coordinate the synthesis of viral DNA and structural proteins. We also consider RNA processing, the addition of a 5'-cap, poly(A) tail, and splicing, the myriad of noncoding RNAs and RNA methylation that can regulate gene expresssion.

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20 октября 2021 г. 22:08:08
02:00:55
Яндекс.Метрика