Beta Sheet, Protein Secondary Structure - Medicinal Chemistry 1.6
Beta sheet is another protein secondary structure, other than alpha helix. Beta sheet forms by joining polypeptide strands together via a hydrogen-bonding network, while the side-chains of amino acids are pointing above or below the sheet.
Just like polypeptide chains, beta sheets are directional as well. The two most common patterns are parallel and anti-parallel. For parallel beta sheets, the N-terminus of one strand is adjacent to the N-terminus of the other stand. For anti parallel beta sheet, the peptide segments run in the opposite direction, in which the N-terminus of one strand is adjacent to the C-terminus of the other strand.
0:00 Secondary structure
0:58 Beta sheet structure
2:38 Parallel vs. anti-parallel beta sheet
--About me--
I am a computational chemist in the pharmaceutical industry. I created the Mole Man Chem channel to explain some basic medicinal and biochemistry concepts because I believe the best way to relearn a concept is through teaching.
Feel free to email me with any questions at molemanchem@gmail.com
--Video lists--
Medicinal chemistry playlist: https://www.youtube.com/watch?v=SNYb7E9oWO4&list=PLK7JMguNBXJOefOP5WFy9AUIsKReOD91I&t=0s
Видео Beta Sheet, Protein Secondary Structure - Medicinal Chemistry 1.6 канала Daniel S.
Just like polypeptide chains, beta sheets are directional as well. The two most common patterns are parallel and anti-parallel. For parallel beta sheets, the N-terminus of one strand is adjacent to the N-terminus of the other stand. For anti parallel beta sheet, the peptide segments run in the opposite direction, in which the N-terminus of one strand is adjacent to the C-terminus of the other strand.
0:00 Secondary structure
0:58 Beta sheet structure
2:38 Parallel vs. anti-parallel beta sheet
--About me--
I am a computational chemist in the pharmaceutical industry. I created the Mole Man Chem channel to explain some basic medicinal and biochemistry concepts because I believe the best way to relearn a concept is through teaching.
Feel free to email me with any questions at molemanchem@gmail.com
--Video lists--
Medicinal chemistry playlist: https://www.youtube.com/watch?v=SNYb7E9oWO4&list=PLK7JMguNBXJOefOP5WFy9AUIsKReOD91I&t=0s
Видео Beta Sheet, Protein Secondary Structure - Medicinal Chemistry 1.6 канала Daniel S.
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