Micronano devices for Biomedical Applications - Xi Xie

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Micro/nano-devices for Biomedical Applications
Professor Xi Xie
Professor, Sun Yat-sen University, China
Group Website: http://seit.sysu.edu.cn/teacher/303
ABSTRACT:

Micro/nano system technology have greatly facilitate the development of bioinformatics research. In the field of bioelectronics and bioinformatics, researches have been greatly attracted by biological system modeling and disease predictions based on the understanding of intracellular protein dynamic expression. We have been focusing on the fundamental research on micro/nano-system for biomedical applications, trying to address the key issues on three levels, from the outside to the inside, in vitro – transdermal – and in vivo, aiming to overcome the key challenge of how to develop bio-safe technology to detect and regulate biological disease: 1) On the in vitro cellular level, we made breakthrough process on the development of nano-devices that could safely penetrate cell membrane, achieving regulation and sensing of the intracellular contents dynamically. 2) On the transdermal level, we systematically developed transdermal theranostic system, achieving precise and in situ detection and therapy of diseases. 3) On the in vivo level, we creatively develop bio-safe implantable theranostic system, achieving safe regulation and sensing of diseases in vivo. Our work holds great promise on facilitating the development of new tools for biomedical sensing detection and biomedical therapy, which would be critically important for the field of bioelectronics.

BIOGRAPHY:

Prof. Xi Xie is currently a full professor in the School of Electronics and Information Technology at Sun Yat-sen University, and is an adjunct professor in the First Affiliated Hospital of Sun Yat-sen University at the meantime. He graduated from Stanford University in USA with PhD degree on 2014, and then worked as a postdoc researcher in the Prof. Robert Langer’s lab at Massachusetts Institute of Technology. On 2016, he started his own research lab at Sun Yat-sen University. Prof. Xi Xie has been focusing on the fundamental research on micro/nano-system for biomedical applications. He has published 54 manuscripts. As corresponding author or first authors, 36 manuscripts have been published on journals including Nature Biomedical Engineering, Nature Nanotechnology, ACS Nano, Advanced Functional Materials and et al. These works were highlighted by Nature series journals for 3 times. He is also applying for more than 38 patents at the meantime. He was awarded by “MIT Technology Reviews Innovators Under 35 China”, and won the “Outstanding Scientific Award of Chinese Institute of Electronics”, and the “Microsystems & Nanoengineering Summit 2019 Young Scientist Award”. Prof. Xi Xie served as the editorial board member in two core journals including Life Science Instruments, and served as the academic members in three academic associations in China.

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