Comparing Alzheimer's and Parkinson's: Understanding Protein Plaques and Gut Bacteria

Comparing Alzheimer's and Parkinson's: Understanding Protein Plaques and Gut Bacteria

Dr. Malu Gomez Tansey explains the similarities between Alzheimer's and Parkinson's, highlighting the role of amyloid and synuclein protein plaques in these neurodegenerative diseases. She discusses how research in Alzheimer's can inform Parkinson's studies, despite different gut bacteria imbalances in each condition.

Tune in for the full episode: Exploring Gut Health's Influence on Neurodegeneration with Dr. Malu Gomez Tansey ▶️https://youtu.be/1mMiJEsKb4E

Malú Gámez Tansey, Ph.D. is the Norman and Susan Fixel Chair in Neuroscience and Neurology and former Director of the Center for Translational Research in Neurodegenerative Disease at the University of Florida. Her lab focuses on the role of inflammation and immune system responses in brain health and neurodegenerative disease with a long-term goal of developing better therapies to prevent and/or delay these diseases. Recent studies from her lab revealed an important role for LRRK2 in regulating Glucorecebrosidase (GCase) activity in peripheral immune cell function in an age- and sex-dependent manner and mutations may confer immunological advantages early in life and accelerated innate immune cell exhaustion with aging.

Dr. Tansey obtained her B.S/M.S in Biological Sciences from Stanford University and her Ph.D. in Cell Regulation from UT Southwestern followed by post-doctoral work in neuroscience at Washington University. As head of Chemical Genetics at Xencor, she co-invented novel soluble TNF inhibitors that have now advanced to clinical trials in Alzheimer’s disease. Dr. Tansey is a fierce advocate for women and other under-represented groups in STEM and has earned several mentoring awards from students and faculty for her efforts in this area.

Connect with Malú Gámez
@MaluTansey on X
Malu Tansey on LinkedIn
https://ctrnd.med.ufl.edu/profile/tansey-maria/

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Видео Comparing Alzheimer's and Parkinson's: Understanding Protein Plaques and Gut Bacteria канала Dr. Urban A. Kiernan