Carcinogenesis, Oncogenes, Tumor suppressor genes

Molecular basis of cancer
Protooncogenes into oncogenes
a. point mutation
b. chromosomal translocation
c. insertion of promotor or enhancer
d. gene amplification

oncogenes produces mutated proteins that causes accelerated cell division and cell growth

antioncogenes or tumoor suppressor genes

Mechanism of p53 tumor suppressor gene
Mechanism of RB Tumor suppressor gene

Видео Carcinogenesis, Oncogenes, Tumor suppressor genes канала Biochemistry by Dr Rajesh Jambhulkar