Chronic Pain Could Finally Be Controlled

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Researchers from University of Pennsylvania, University of Pittsburgh, and Scripps Research have discovered a new brain circuit that may control chronic pain.

👉 What they found:

Special neurons called Y1 receptor neurons (Y1R)
Located in the brainstem (lateral parabrachial nucleus)
These neurons stay active during long-term pain

👉 The breakthrough:

The brain has a built-in “override system”

Hunger, fear, and survival signals can reduce pain
A molecule called neuropeptide Y (NPY) helps “turn down” pain signals

👉 Why this matters:

Chronic pain affects tens of millions of people
Current treatments are often ineffective
This discovery opens the door to completely new therapies

👉 Future possibilities:

Targeting these neurons for next-gen painkillers
Using brain signals as a biomarker for chronic pain
Even behavioral methods like exercise or meditation may help regulate pain

👉 The big idea:
Pain may not just be in the body — it’s controlled by the brain.

👉 The big question:
Could we one day “switch off” chronic pain?

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Видео Chronic Pain Could Finally Be Controlled канала Xenon Lab | Science & Technology