Essential Unlockables - The Complete Guide (The Binding of Isaac Afterbirth+)

So apparently I make Isaac guides now?
Sections:
0:00 - Intro
1:09 - Azazel
2:44 - Eden
3:16 - Mom's Knife
4:09 - Blank Card
5:33 - The D6
6:48 - The Polaroid
7:42 - D20
9:19 - Bloody Penny
10:19 - Counterfeit Penny
11:35 - Swallowed Penny
13:30 - Jera
14:43 - Algiz
16:29 - Perthro
17:36 - Ansuz
18:21 - Dagaz
19:34 - Chaos Card
21:04 - Death's Touch
22:10 - Epic Fetus
26:08 - Outro
This video has been an insanely long time in the making (at least by my standards, since it took 3-4x longer than my previous guide), and I felt really tired after finally finishing it, so I won't start work on any new guide for at least a few weeks so that I don't burn out.

That said, if there is demand (especially around the Repentance release period), new guides will almost certainly come out.

Special thanks to Adrian Nuñez, who gave me the idea for this guide as well as a lot of encouraging words. Sorry for the 3-month wait, Adrian!

As before, feedback and constructive criticism is appreciated, and I'd love to hear what guides you think I should make next.
Chaos Card guide: https://www.youtube.com/watch?v=Qy1Y6G1gCyQ
Challenges on the Wiki: https://bindingofisaacrebirth.gamepedia.com/Challenges
Sources:

REEEEEE Sound Effect
https://www.youtube.com/watch?v=-HtNaVFpw4Q

THAT Crowd Gasp
https://www.youtube.com/watch?v=V5eaDhCVNJU

[Spoiler] reward for a [Spoiler] achievements isn't actually bad like some people assume (details in comments)
https://www.reddit.com/r/bindingofisaac/comments/5m0eir/spoiler_reward_for_a_spoiler_achievements_isnt/

Drum Roll - Gaming Sound Effect (HD)
https://www.youtube.com/watch?v=Ek56AgxwybI
Footage and editing by yours truly, images mostly from the Wiki (and some Twitch emotes)

Видео Essential Unlockables - The Complete Guide (The Binding of Isaac Afterbirth+) канала Meatnyan