Trying to conceive and IVF Failure: Did uterine inflammation cause your failure?

Dr Randy Morris MD-The BOARD CERTIFIED fertility expert with weekly TTC tips on InfertilityTV

In a previous episode of Infertility TV, I discussed checking for inflammation in the body with a blood test. If you haven’t seen that episode, put it on your playlist to watch next.

In this episode, I am going to discuss inflammation in the uterus. Inflammation is a process by which the body's white blood cells and the substances they produce protect us from infection with foreign organisms, such as bacteria and viruses. Inflammation in the uterus is called chronic endometritis.

Most of the time, IVF implantation failure is caused by abnormal embryos. If you haven’t done preimplantation genetic screening on your embryos, then that is the first step. But if you have already done that and you still didn’t get pregnant, it’s time to look for chronic endometritis.

Most women with chronic endometritis don’t have any symptoms. Diagnosing it can be a bit tricky. Here is what we do at IVF1

First, we look inside the uterus using hysteroscopy. We are looking for certain patterns that are common with chronic endometritis. Here is a patient in which we saw something called micro-polyps - a strong indicator for inflammation. You have to use hysteroscopy with magnification find these. Other methods for studying the uterus such as an HSG or saline ultrasound will not be able to see these abnormalities.

Next we use the hysteroscope to take some biopsies of the uterine lining. We can look at these pieces of tissue under the microscope for plasma cells. Plasma cells confirm that you have inflammation in the uterus.

Finally, we will also do testing on the uterine tissue specimens to look for bacteria that might be causing the inflammation.

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Видео Trying to conceive and IVF Failure: Did uterine inflammation cause your failure? канала Infertility TV