Microfluidics Interviews #1: In situ chemistry

Can you create a drug directly in a living organism? 💊 Yes, by combining microfluidics with acoustics and organic chemistry! We interview Marine Bézagu, PhD, to know more.
↓ More infos and links in the description ↓

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LINKS:

French version: https://www.youtube.com/watch?v=MaVk_xWRtCU
Subscribe to the channel : https://youtube.com/thelutetiumproject
Follow us on Twitter : https://twitter.com/TheLuProject
Visit our website: https://www.lutetium.paris/en

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MORE ABOUT THE INTERVIEWEE:

Marine Bézagu is an alumnus of ESPCI Paris, and of Université Pierre et Marie Curie, where she obtained a master's degree in Molecular Chemistry. In 2015, she defended her PhD thesis, titled "Ultrasound-induced chemical reactions and local mixing : towards targeted chemotherapy", that was conducted between the Laboratoire de Chimie Organique, the Gulliver lab and the Institut Langevin at ESPCI Paris. She kept working on this project as a post-doctoral researcher at Institut Langevin for an extra year.
Between 2016 and 2020, she worked as a research scientist in chemical formulation for ADOCIA, a company specialized in developing innovative formulations for therapeutical molecules. She recently moved to a Research & Development Project Manager position at InnovaFeed, a young biotech company that commercializes insect proteins.

Marine Bézagu on LinkedIn: https://fr.linkedin.com/in/mbezagu

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FEATURED ARTICLE:

Marine Bezagu, Claudia Errico, Victor Chaulot-Talmon, Fabrice Monti, Mickael Tanter, Patrick Tabeling, Janine Cossy, Stellios Arseniyadis, & Olivier Couture, High Spatiotemporal Control of Spontaneous Reactions Using Ultrasound-Triggered Composite Droplets, J. Am. Chem. Soc. 2014, 136, 20, 7205–7208
https://pubs.acs.org/doi/abs/10.1021/ja5019354

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VIDEO BREAKDOWN:

00:00 Targeted drug delivery
01:27 In situ chemistry: principle
03:33 Encapsulation method
05:30 Triggering the reaction
06:55 Model experiment: principle
07:43 Fluorescence
07:57 Model experiment: realization
08:39 Local synthesis of anticancer drugs
09:46 Conclusion

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CREDITS:

Host:
Guillaume Durey

Researcher:
Marine Bézagu

Script:
Martin Cattoen, Guillaume Durey, Mathias Kasiulis

Director:
Hoon Kwon

Animators:
Benjamin Alardin, Hoon Kwon

Editors:
Guillaume Durey, Hoon Kwon

Studio, visual identity:
Juliette Nier

Theme music:
Pierre David

Production:
Guillaume Durey, Mathias Kasiulis

This video was shot on September 16th, 2015.
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The Lutetium Project is a PSL students’ initiative conducted as part of IDEX ANR-10-IDEX-0001-02 PSL and funded by:
PSL Research University – https://www.univ-psl.fr
ESPCI Paris – https://www.espci.fr
Espace des sciences Pierre-Gilles de Gennes – https://www.espgg.org
ESPCI Alumni – https://espci.alumni.paris
le Fonds ESPCI Paris – https://www.fonds-espci-paris.org/
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Видео Microfluidics Interviews #1: In situ chemistry канала The Lutetium Project