Proteins and Enzymes in Eukaryotic Transcription

In this video we have discussed about the Proteins and Enzymes in Eukaryotic Transcription.
RNA polymerase (ribonucleic acid polymerase), both abbreviated RNAP or RNApol, official name DNA-directed RNA polymerase, is an enzyme that synthesizes RNA from a DNA template. RNAP locally opens the double-stranded DNA (usually about four turns of the double helix) so that one strand of the exposed nucleotides can be used as a template for the synthesis of RNA, a process called transcription.

Eukaryotes have multiple types of nuclear RNAP, each responsible for synthesis of a distinct subset of RNA. All are structurally and mechanistically related to each other and to bacterial RNAP:

RNA polymerase I synthesizes a pre-rRNA 45S (35S in yeast), which matures into 28S, 18S and 5.8S rRNAs which will form the major RNA sections of the ribosome.[27]
RNA polymerase II synthesizes precursors of mRNAs and most snRNA and microRNAs.[28] This is the most studied type, and, due to the high level of control required over transcription, a range of transcription factors are required for its binding to promoters.
RNA polymerase III synthesizes tRNAs, rRNA 5S and other small RNAs found in the nucleus and cytosol.

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