Vilobelimab for Severe COVID-19 and Possibly Other Diseases

Roger Seheult, MD of MedCram examines vilobelimab in the treatment of severe COVID with possible applications in the treatment of other diseases. See all Dr. Seheult's videos at: https://www.medcram.com/?utm_source=Youtube&utm_medium=Video&utm_campaign=Video+Link+Clicks&utm_term=Vilobelimab+for+Severe+COVID-19+and+Possibly+Other+Diseases&utm_content=MVqeeVlmWZ4

(This video was recorded on May 7th, 2023)

Roger Seheult, MD is the co-founder and lead professor at https://www.medcram.com/?utm_source=Youtube&utm_medium=Video&utm_campaign=Video+Link+Clicks&utm_term=Vilobelimab+for+Severe+COVID-19+and+Possibly+Other+Diseases&utm_content=MVqeeVlmWZ4

He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.
LINKS / REFERENCES:

Controlling the anaphylatoxin C5a in diseases requires a specifically targeted inhibition (Clinical Immunology) | https://www.sciencedirect.com/science/article/abs/pii/S1521661617301729?via%3Dihub

The anti-C5a antibody vilobelimab efficiently inhibits C5a in patients with severe COVID-19 (Clinical and translational science) | https://pubmed.ncbi.nlm.nih.gov/35029045/

Anti-C5a antibody (vilobelimab) therapy for critically ill, invasively mechanically ventilated patients with COVID-19 (PANAMO): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial (Lancet Respir Med) | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9451499/pdf/main.pdf

Treatment With Anti-C5a Antibody Improves the Outcome of H7N9 Virus Infection in African Green Monkeys (Clinical infectious diseases) | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112341/

FACT SHEET FOR HEALTHCARE PROVIDERS: EMERGENCY USE AUTHORIZATION FOR GOHIBIC (FDA) | https://www.fda.gov/media/166824/download

COVID-19 Ventilator Course: Learn or Review Mechanical Ventilation (MedCram) | https://www.medcram.com/courses/COVID19-ventilator-mechanical-ventilation?utm_source=Youtube&utm_medium=Video&utm_campaign=Video+Link+Clicks&utm_term=Vilobelimab+for+Severe+COVID-19+and+Possibly+Other+Diseases&utm_content=MVqeeVlmWZ4
All coronavirus updates are at MedCram.com (including more discussion on delta variant covid, COVID Delta, COVID children, natural immunity COVID 19, and more).

MedCram Update 46: https://youtu.be/EFRwnhfWXxo

MedCram Update 47: https://youtu.be/H1LHgyfPPQ8

MedCram Update 132: https://youtu.be/9OZZ6_M4OB0
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Video Produced by Kyle Allred
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Видео Vilobelimab for Severe COVID-19 and Possibly Other Diseases канала MedCram - Medical Lectures Explained CLEARLY