Virology Lectures 2021 #6 - RNA Directed RNA Synthesis

Cells have no enzymes to copy long viral RNAs, so a virus-coded RNA dependent RNA polymerase is needed. In this lecture we discuss the principles and mechanisms of RNA synthesis by these enzymes, including priming of RNA synthesis, how mRNA and genomes are produced in infected cells, and the switch from synthesis of mRNAs to genomes. This discussion sets the state for a consideration of the two sources of diversity for RNA viruses - polymerization errors and recombination - that have enabled their reproductive success.

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Видео Virology Lectures 2021 #6 - RNA Directed RNA Synthesis канала Vincent Racaniello