Proliferative to invasive switch mediated by srGAP1 downregulation by activation of TGF-β2 signaling

In this episode of Research in Action, Javier Bravo-Cordero from the Icahn School of Medicine at Mount Sinai discusses his work using high resolution in vivo microscopy to study how breast cancer cells balance proliferative and invasive signals during dissemination and metastasis.

Read the related paper in Cell Reports: https://www.cell.com/cell-reports/fulltext/S2211-1247(22)01190-1

Research in Action breaks down cutting-edge imaging research published in Cell Press journals, giving scientists from across a broad spectrum of scientific disciplines a look into how these techniques were created and what discoveries they enabled.

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Видео Proliferative to invasive switch mediated by srGAP1 downregulation by activation of TGF-β2 signaling канала Cell Press