COVID-19: The DEFINITIVE Antibody Studies: Why The Tests Don’t Work

On the 25th June, the Cochrane Review was released - a study searching 11,000 publications and 16,000 samples to evaluate the functionality of antibody testing for the coronavirus. But the data is not as conclusive as you might think - and my own study of 411 long haulers, along with fresh pre-print studies from teaching hospitals in the UK draw a very different picture. These antibody tests are not as effective as their manufacturers would have you believe. But why?

0:00 Introduction
0:26 The Issue
1:36 The Cochrane Review
7:30 Hypothesis
9:40 The Long Haulers Study
16:17 Conclusion

References:

MEDIA:

BMJ: Cochrane Review:
https://www.bmj.com/content/369/bmj.m2469

Reuters
https://in.mobile.reuters.com/article/amp/idINKBN23X1BZ?__twitter_impression=true&fbclid=IwAR2V51qWn-asR_cN37yxBw3wW5jrIV4YZY4zCSNI8CH9Hv2GCMz4XEAknVk

Prof. Jon Deeks tweet thread:
https://threadreaderapp.com/thread/1276180391217561607.html

Science Daily - Robust evidence for CFS:
https://www.sciencedaily.com/releases/2015/02/150227144903.htm

The Guardian, Debbie Bogaert
https://www.theguardian.com/commentisfree/2020/jun/28/coronavirus-long-haulers-infectious-disease-testing?CMP=Share_iOSApp_Other

STUDIES:

Cochrane Review:
https://www.cochrane.org/news/new-cochrane-review-assesses-how-accurate-antibody-tests-are-detecting-covid-19

https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD013652/full

University Hospitals Birmingham / Richter et al - healthcare workers:
https://www.medrxiv.org/content/10.1101/2020.05.18.20105197v1.full.pdf

UCLH Sapphire study / Bampoe et al - Ob/Gyn hospital study:
https://www.medrxiv.org/content/10.1101/2020.06.24.20139352v1

Long et al: Asymptomatic vs Symptomatic:
https://www.nature.com/articles/s41591-020-0965-6

Interfamilial study, Gallais et al:
https://www.medrxiv.org/content/10.1101/2020.06.21.20132449v1?fbclid=IwAR3N0XxkSKMrSMpF3PrDxwrnVcb_43zm-npfnapr9UsoudRm29fPwFUnV9c

Robust T Cell Immunity, Sekine et al (Sweden)
https://www.biorxiv.org/content/10.1101/2020.06.29.174888v1

Systemic mucosal study, Cervia et al (Switzerland)
https://www.biorxiv.org/content/10.1101/2020.05.21.108308v1

Preprint - Spike Protein
https://www.sciencemag.org/news/2020/03/new-blood-tests-antibodies-could-show-true-scale-coronavirus-pandemic
https://www.medrxiv.org/content/10.1101/2020.03.17.20037713v1

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