Lecture on Cervical Pathology Explained: Anatomy, Cervicitis, CIN, HPV & Cervical Cancer I MBBS

This comprehensive medical lecture provides an in-depth understanding of cervical pathology, guiding viewers from basic anatomy and physiology to the development, diagnosis, and prevention of cervical cancer. Ideal for MBBS students, healthcare professionals, and anyone seeking detailed knowledge on this critical topic.

Key Learning Objectives & Topics Covered:

Cervical Anatomy & Physiology:
Detailed exploration of the transformation zone and its significance in HPV infection susceptibility [05:01, 05:18].
The crucial role of estrogen and lactobacilli in maintaining a healthy cervical environment and pH [05:23, 06:17].
Cervicitis - Inflammation of the Cervix:
Pathogenesis, including the impact of pH alterations and various infectious agents [07:35, 08:30].
Microscopic features and findings in chronic cervicitis [09:21].
Precursor Lesions - CIN & SIL:
Understanding the classification systems: Cervical Intraepithelial Neoplasia (CIN) and Squamous Intraepithelial Lesion (SIL) [11:22, 18:44].
Cellular characteristics of dysplasia and koilocytic atypia (HPV effect) [13:39, 14:42].
The natural history and progression from CIN to invasive cervical carcinoma [16:33, 17:22].
Cervical Carcinoma (Cervical Cancer):
Role of HPV: The critical involvement of Human Papillomavirus (HPV) in cervical cancer development. Discussion on high-risk HPV types and viral oncogenes/proteins like E5, E6, and E7 and their mechanisms (e.g., p53 and Rb suppression) [20:33, 24:50].
Histological Types: Detailed overview of different types of cervical cancer:
Squamous Cell Carcinoma
Adenocarcinoma
Adenosquamous Carcinoma
Neuroendocrine Carcinoma [21:22, 26:54].
Diagnosis, Staging & Treatment:
Clinical staging of cervical cancer [31:20].
Overview of various treatment modalities [32:34].
Screening & Prevention:
Screening Methods: Emphasis on the importance of Pap smears (cervical cytology) and HPV DNA testing for early detection [33:03, 33:54].
Screening Guidelines: Recommendations for Pap smear screening frequency and appropriate follow-up protocols for abnormal results [36:41, 38:32].
Prevention: The vital role of HPV vaccination in primary prevention of cervical cancer [40:25].
This lecture aims to equip viewers with a thorough understanding of the spectrum of cervical diseases, emphasizing the link between HPV infection and cervical cancer, and the importance of screening and vaccination in public health.
SANTINIKETAN MEDICAL COLLEGE & HOSPITAL
Real Classroom Demonstration/Lecture
On: PATHOLOGY by Dr. Sriranjan Mukherjee
(MBBS Batch: 2023-24)
Conducted on: 02-06-25

Видео Lecture on Cervical Pathology Explained: Anatomy, Cervicitis, CIN, HPV & Cervical Cancer I MBBS канала Santiniketan Medical College