Immune Response Explained: T-Cell Activation

Every day billions of tiny invaders called pathogens want to make our bodies their new homes. Luckily, we have a powerful army of specialized organs, cells, and tissues that work together to protect us. This is your body's immune system. Within this complex system is type of lymphocyte called a T-cell. This video will introduce you to Helper and Cytotoxic T-cells, and describe the mechanism by which they are activated when encountered by a pathogen. If you wish to know more about this remarkable process, make sure to stay tuned so we can demystify T-cells together!

This video was made by Demystifying Medicine students Navroop
Gosal, Jiayi Mo, Xiuyuan Song and Sara Warsi, in collaboration with the McMaster Demystifying Medicine Program.

Copyright McMaster University 2020
References:
Cavanagh, M. (n.d). T cell Activation. British Society for Immunology. Retrieved from https://www.immunology.org/public-information/bitesized-immunology/systems-and-processes/t-cell-activation

Gaudino, S. J., & Kumar, P. (2019). Cross-talk between antigen presenting cells and T cells impacts intestinal homeostasis, bacterial infections, and tumorigenesis. Frontiers in immunology, 10, 360. https://doi.org/10.3389/fimmu.2019.00360
IQWiG (Institute for Quality and Efficiency in Health Care). (2020, July 30). The innate and adaptive immune systems. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK279396/
Sauls, R. S., McCausland, C., & Taylor, B. N. (2019). Histology, T-Cell Lymphocyte. In StatPearls [Internet]. StatPearls Publishing.

Smith-Garvin, J. E., Koretzky, G. A., & Jordan, M. S. (2009). T cell activation. Annual review of immunology, 27, 591-619. DOI: 10.1146/annurev.immunol.021908.132706

Storey, M., & Jordan, S. (2008). An overview of the immune system. Nursing Standard, 23 (15-17):47-56. DOI: 10.7748/ns2008.12.23.15.47.c6738

Видео Immune Response Explained: T-Cell Activation канала Demystifying Medicine