Nogo-A regulation of ceramide biosynthesis protects the heart from failure - July 27th 2020

Annaritta di Lorenzo from Weill Cornell Medical College, New York, USA examines the role of Nogo-A - a negative regulator of de novo sphingolipid synthesis - in heart failure. She discusses how loss of Nogo-A leads to dramatic increases exacerbation of pathological cardiac hypertrophy and dysfunction following pressure overload, correlating with increased ceramide levels and suppression of autophagy.

Видео Nogo-A regulation of ceramide biosynthesis protects the heart from failure - July 27th 2020 автора Planetary Prodigies