YASCP: Next-Gen Pipeline for Ultra-Large Scale scRNA Analysis

Matiss Ozols introduces the YASCP tool, designed for ultra-large scale single-cell RNA quality control and analysis. Learn how YASCP contributes to projects like the Cardinal project, setting new standards for studying millions of cells and opening doors for impactful research. Title: YASCP: A next-gen pipeline for ultra-large scale scRNA quality control & analysis Speaker: Matiss Ozols, Human Genetics, Wellcome Sanger Institute Abstract: The YASCP tool (github.com/wtsi-hgi/yascp) was designed with a straightforward goal: to create a massive, easily accessible bank of detailed cell data from blood samples of UKBiobank (UKBB) and East London Genes and Health (ELGH) participants (Cardinal). YASCP was written to support the Cardinal project, but is applicable to many other projects. We wanted to closely study and document the unique features of millions of these cells - a project of a scale not seen before. Using YASCP, the Cardinal project successfully achieved this, analysing data from 5,000 UKBB and 1,500 ELGH individuals, giving us a deeper understanding of their health and genetics. This success sets a new standard and opens doors for other big projects. For instance, YASCP might soon help the Jaguar project to understand the detailed cellular makeup of people from Latin America. And throughout all this, we can trust the accuracy and reliability of YASCP, thanks to the strong foundation provided by Nextflow.

Видео YASCP: Next-Gen Pipeline for Ultra-Large Scale scRNA Analysis автора Euro-Explorations