SEEING INSIDE A COVID19 INJURED LUNG

Using the world’s brightest X-ray source, the ESRF-EBS, ESRF and UCL scientists are developing a technique to use Hierarchical Phase-Contrast Tomography (HiP-CT) to image with cellular resolution anywhere in a human body. This video shows feasibility results using HiP-CT to image the injury done to the lung of a 54 year old Covid-19 victim to try and help understand how the disease affects oxygen exchange spanning from large airways to the finest microvasculature. (Credit Paul Tafforeau).

Human Organ Project imaging of a whole left lung lobe showing injury due to Covid-19 using the new capabilities of ESRF-ESB. Showing aerated air spaces (blue), occluded pulmonary blood vessels (yellow) and non-occluded pulmonary blood vessels (red).
Video produced by Paul Tafforeau.

Results for scientific and medical research use only. This video is under press embargo until further notice, please do not copy. The Human Organ Project originated from a group trying to understand how Covid-19 injures our organs, and how they recover, and is now trying to develop the technique to map our organs in health and disease to better understand them from a system (anatomical) level down to sub-cellular function.

Project Investigators/contributors: Peter D. Lee and Claire Walsh (UCL), Paul Tafforeau (ESRF), Danny Jonigk (Hannover), Maximilian Ackermann (Mainz), Will Wagner (Heidelberg), Joe Jacob and Simon Walker-Samuel (UCL), Mark Kuehnel and Christopher Werlein (Hannover), Alexandre Bellier (LADAF), and many others helping.
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Видео SEEING INSIDE A COVID19 INJURED LUNG канала ESRFsynchrotron