1 in 7 melanoma patients genetically predisposed

A new study from the Cleveland Clinic, co-led by Dr. Joshua Arbesman, reveals that genetics may play a more significant role in melanoma risk than previously thought, with about 15 percent of patients showing a pathogenic variant that increases cancer risk. The research found that two-thirds of the significantly altered genes were not previously associated with melanoma, suggesting that family history might be a more crucial risk factor than sun exposure in some cases. This discovery could lead to changes in how doctors screen for melanoma and expand eligibility for genetic testing, potentially affecting insurance coverage. Additionally, it may alleviate some of the guilt that patients feel about past sun exposure.

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