Bronchodilators Part 1: Principles of Respiratory Airflow and Development of Selective Drugs

With immunomodulation covered, it's time to dive into pharmacology of pulmonary activity. First up is bronchodilators. These address resistance in the bronchus and bronchioles that impede respiration, such as with asthma, emphysema, and bronchitis. This can be achieved through beta-2 adrenocepter agonism and muscarinic receptor antagonism. What are these receptors, what are their endogenous agonists, and how do bronchodilators interact with these receptors?

Script by Michael Keith

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