Nutrigenomics and Precision Lifestyle Medicine

Lessons from Big Data Made Simple with Opus23 Explorer – Presented by David M. Brady, ND, DC, CCN, DACBN. IFMCP, FACN.
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While complex chronic disease is growing at epidemic proportions in the Western industrialized counties, clinical medicine is generally at a loss stem the tide of this epidemic. Big data, machine learning and artificial intelligence presents great hope in unraveling some of the causes by analyzing connections between specific patterns involving genomics, microbiomics, proteomics, and metabolomics and the development of specific disorders. However, big-data is complicated and involves massive numbers of variables and complex networks. How does a clinician make any sense of this emerging information and leverage it in their clinical approach to complicated patient cases? This presentation will look at some of these issues from a practicing clinician’s perspective and will focus on how to parse through and curate meaningful genomic information (SNPs) utilizing a state-of-the-art medical informatics platform, Opus-23 Explorer, including the deciphering of complex multi-SNP network mappings. The Opus-23 Explorer platform was developed by Dr. Peter D’Adamo at the Center of Excellence in Generative Medicine at the University of Bridgeport and is now being used both by researchers in major academic centers of excellence and by clinicians in private practice settings internationally.

Objectives:
1. Appreciate the current epidemiologic trends in chronic complex disease and how big-data analytics may help in slowing this epidemic.

2. Understand the linkage and association between the prevalence of various chronic complex diseases and metabolic abnormalities and various genomic patterns in individuals through the lessons learned from population-wide big-data analytics.

3. Appreciate the available clinical laboratory testing and analysis related to “omics” and how to make big-data work for you as a clinician.

4. Understand the navigation and curation of personal genomic data-sets using the Opus-23 Explorer medical informatics platform and portal.

5. Become enlightened on the determination of new therapeutic strategies for various chronic complex diseases and metabolic abnormalities utilizing personalized genomic data-sets and lessons from population-wide big-data analysis.
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Originally presented February 2020 at Integrative Healthcare Symposium (IHS)-2020.
Visit Integrative Healthcare Symposium at: https://www.ihsymposium.com

Learn more about GenomicInsight® and Opus23 Explorer at: https://www.diagnosticsolutionslab.com/tests/genomicinsight

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