Next-Generation T-Cell Therapeutics Set Sights on Cancers, Autoimmune Disorders and More

T cells – immune cells that patrol our bodies in search of trouble -- have become a central focus for UC San Francisco scientists working on living cell therapies, an approach that views cells themselves as a form of medicine.
T cells actually include a diverse group of cells with specialized roles. So-called killer T cells attack foreign invaders, while helper T cells release signals to orchestrate the overall immune response. Once a threat is neutralized, another subset — the regulatory T cells, produce anti-inflammatory factors that shut down the immune response. T cells’ range of behaviors and their ability to survive for years in our bodies have made them attractive candidates for living cell therapies. UCSF researchers are finding ways to modify T cells to enhance our immune response against cancers and viral infection and to quiet our immune response in autoimmune disorders. Harnessing the power of the body’s own systems to create adaptive therapeutics is at the core of the University’s new Living Therapeutics Initiative, which will provide new facilities, resources and leadership in this area.

Additional video provided by Alex Ritter

Видео Next-Generation T-Cell Therapeutics Set Sights on Cancers, Autoimmune Disorders and More канала UC San Francisco (UCSF)