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Night Shifts Disable DNA Repair: WHO

How many unrepaired DNA errors has each night shift already left behind?
Night shifts suppress the gene that triggers DNA repair during sleep — WHO classifies this as a probable carcinogen.

Circadian rhythm disruption impairs DNA damage response and increases genomic instability over time. Research links night work to elevated cancer risk through suppressed melatonin production and disrupted cell cycle regulation. Shift workers experience compounded biological stress that sleep recovery alone cannot reverse.

🔬 Research:
Research: WHO/IARC Monographs — Lancet Oncology, 2007 & Vol.124, 2019
Mechanism: Oncogene (Nature), 2023 — BMAL1 in DNA repair

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