Single-Molecule Method Reveals Functional Inheritance of EGFRs in Extracellular Vesicles

The quantity and protein–protein interaction (PPI) strengths of epidermal growth factor receptors (EGFRs) derived from extracellular vesicles (EVs) and the original lung adenocarcinoma cells are determined using single‐molecule immunolabeling and co‐immunoprecipitation methods. The EGFR PPI strengths measured for EVs generally show tight correlation with those determined for the original cells.

This is reported by Mi Sook Sung, Jik-Han Jung, Cherlhyun Jeong, Tae-Young Yoon, and Ji-Ho Park in the article https://doi.org/10.1002/smll.201802358.

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Видео Single-Molecule Method Reveals Functional Inheritance of EGFRs in Extracellular Vesicles канала Advanced Science News