A Man Ate 100 Zinc Vitamin C Gummies Everyday. This Is What Happened To His Spinal Cord.

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Menkes Disease Case courtesy of Dr Prashant Gupta , Radiopaedia.org, rID: 18273

These cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.

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References:

The Essential Toxin: Impact of Zinc on Human Health. Int J Environ Res Public Health. 2010 Apr; 7(4): 1342–1365. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872358/

No contribution of ascorbic acid to renal calcium oxalate stones. Ann Nutr Metab. 1997;41(5):269-82. https://pubmed.ncbi.nlm.nih.gov/9429689/

Acute oxalate nephropathy after massive ascorbic acid administration. Arch Intern Med. 1985 May;145(5):950-1. https://pubmed.ncbi.nlm.nih.gov/3994472

Hypocupremia induced by zinc therapy in adults. JAMA. 1978 Nov 10;240(20):2166-8. https://pubmed.ncbi.nlm.nih.gov/359844/

Mammalian zinc homeostasis: requirement for RNA and metallothionein synthesis. Biochem Biophys Res Commun. 1975 Jun 16;64(4):1215-23. https://pubmed.ncbi.nlm.nih.gov/1137597/

Copper deficiency myelopathy produces a clinical picture like subacute combined degeneration. Neurology. 2004;63(1):33. https://pubmed.ncbi.nlm.nih.gov/15249607/

Motor neuron disease associated with copper deficiency. Muscle Nerve. 2006;34(6):789. 

Case of sensory ataxic ganglionopathy-myelopathy in copper deficiency. J Neurol Sci. 2009;277(1-2):184. 

Ascorbic Acid Supplements and Kidney Stone Incidence Among Men: A Prospective Study. https://jamanetwork.com/article.aspx?articleid=1568519

An Element of Unsteadiness. N Engl J Med 2017; 377:1379-1385.

Ascorbic Acid Intake and Oxalate Synthesis. Urolithiasis. 2016 Aug; 44(4): 289–297. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946963

Copper deficiency myelopathy: a report of two cases. J Spinal Cord Med 2015;38:559-562

Copper deficiency myelopathy (human swayback). Mayo Clin Proc 2006;81:1371-1384

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