SULFONYLUREAS MECHANISM OF ACTION EXPLAINED *ANIMATED*
In this video i explain the mechanism of action of sulfonylureas witch are a very popular class of treatment for type II diabetes.
sulfonylureas main mechanism of action is blocking the ATP sensitive potassium channels which are located on the cell membrane of the beta cells in the pancreas, blocking these channels will subsequently lead to depolarization of the cell witch in terms will open another type of channels on the cell membrane which are calcium channels, voltage sensitive calcium channels open up after the depolarization happens witch allows the exocytosis of insulin from beta cells into the blood stream.
sulfonylureas consist of 3 generations
Diabetes and Insulin video: https://www.youtube.com/watch?v=SgVVGs7nqZA&t=78s
Видео SULFONYLUREAS MECHANISM OF ACTION EXPLAINED *ANIMATED* канала Pill Whiteboard
sulfonylureas main mechanism of action is blocking the ATP sensitive potassium channels which are located on the cell membrane of the beta cells in the pancreas, blocking these channels will subsequently lead to depolarization of the cell witch in terms will open another type of channels on the cell membrane which are calcium channels, voltage sensitive calcium channels open up after the depolarization happens witch allows the exocytosis of insulin from beta cells into the blood stream.
sulfonylureas consist of 3 generations
Diabetes and Insulin video: https://www.youtube.com/watch?v=SgVVGs7nqZA&t=78s
Видео SULFONYLUREAS MECHANISM OF ACTION EXPLAINED *ANIMATED* канала Pill Whiteboard
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