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Enzyme Kinetics & Drug Activity Graph | Inspiring Mindz Coaching #studywithIM

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Enzyme kinetics is the study of the chemical reactions that are catalysed by enzymes. In enzyme kinetics, the reaction rate is measured and the effects of varying the conditions of the reaction are investigated. Studying an enzyme's kinetics in this way can reveal the catalytic mechanism of this enzyme, its role in metabolism, how its activity is controlled, and how a drug or an agonist might inhibit the enzyme.

Enzymes are usually protein molecules that manipulate other molecules—the enzymes' substrates. These target molecules bind to an enzyme's active site and are transformed into products through a series of steps known as the enzymatic mechanism

E + S ⇄ ES ⇄ ES* ⇄ EP ⇄ E + P
These mechanisms can be divided into single-substrate and multiple-substrate mechanisms. Kinetic studies on enzymes that only bind one substrate, such as triosephosphate isomerase, aim to measure the affinity with which the enzyme binds this substrate and the turnover rate. Some other examples of enzymes are phosphofructokinase and hexokinase, both of which are important for cellular respiration (glycolysis).

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Видео Enzyme Kinetics & Drug Activity Graph | Inspiring Mindz Coaching #studywithIM канала InspiringMindz Coaching
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27 июня 2020 г. 20:30:03
00:22:44
Яндекс.Метрика