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Sequence Alignment Explained | Local vs Global Alignment | Dot Matrix Plot | Bioinformatics #ai

In this video, we explain Sequence Alignment in Bioinformatics in a simple and exam-oriented manner. You will clearly understand the difference between Local and Global Alignment, the Dot Matrix (Dot Plot) method, and online tools available for dot plot analysis.

📌 Topics Covered:
What is Sequence Alignment?
Global Alignment (Needleman–Wunsch) – concept & applications
Local Alignment (Smith–Waterman) – concept & applications
Key differences: Local vs Global Alignment
Dot Matrix / Dot Plot method – principle & interpretation
Identification of repeats, inverted repeats & conserved regions
Online Dot Plot Tools & Programs:
Advantages & limitations of dot plot method

🎯 Useful for:
BSc / MSc Life Sciences & Biotechnology
CSIR-NET, GATE, CUET-PG, ICMR, DBT exams
Beginners in Bioinformatics

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