Researchers turn human skin cells into eggs -- but not yet usable ones

(30 Sep 2025)
ASSOCIATED PRESS
ARCHIVE London, UK - 14 August 2013

1. Pan of embryologists in fertility clinic
2. Pan from screen showing embryo to embryologist
3. Zoom out from embryo
4. Close of intra-cytoplasmic sperm injection (ICSI) procedure being done at Create Health Clinic

ASSOCIATED PRESS
Portland, Oregon, US - 30 September 2025
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5. SOUNDBITE (English) Professor Shoukhrat Mitalipov, Director Embryonic Cell and Gene Therapy, Oregon Health & Science University
"So we report here actually during this procedure we develop the so-called, experimental cell division procedure where the egg cell can get rid of half or sometimes you know, portion of the chromosomes and resulting in the embryo will have actually normal 46, chromosomes."

ASSOCIATED PRESS
ARCHIVE: New York, US – 3 October 2013

6. Various of lab technicians examining eggs and embryos under microscopes
7. Close of ICSI procedure
8. Close of screen showing ICSI procedure

ASSOCIATED PRESS
Portland, Oregon, US - 30 September 2025
VIDEO CALL

9. SOUNDBITE (English) Professor Shoukhrat Mitalipov, Director Embryonic Cell and Gene Therapy, Oregon Health & Science University
"But so far, I think the system is doing it wrong, even though we're getting rid of half of chromosomes, but it matters which chromosomes remain inside. So that's actually, our ongoing research, to kind of help the egg to sort out what, what chromosomes actually keep inside."

ASSOCIATED PRESS
ARCHIVE : London, UK - 14 August 2013

10. Screen showing embryo
11. Researcher looking through microscope next to screen showing embryo
12. Close of embryo in petri dish

ASSOCIATED PRESS
Portland, Oregon, US - 30 September 2025
VIDEO CALL

13. SOUNDBITE (English) Professor Shoukhrat Mitalipov, Director Embryonic Cell and Gene Therapy, Oregon Health & Science University
"In today's in-vitro fertilization clinics probably more than half of patients we see are due to this either advanced maternal age when they cannot conceive with their own eggs, and they try many, many times to do this in-vitro fertilization procedure, sometimes up to ten times with their own eggs. And eventually, of course, they give up and take donor egg. So the procedure we're developing, as I mentioned, would allow them to have a genetically related child. In this case you know there are plenty of skin cells and we only need a small pinch to make and multiply them. So I think despite the difficulties now - you know, science is advancing ahead, we have more and more new technologies available for us to do research and eventually, I believe we'll solve these, these issues you know, still remaining ahead and in future the in vitro fertilization I believe, will use this technology one way or another."

ASSOCIATED PRESS
ARCHIVE: New York, US – 3 October 2013

14. Technicians in lab
15. Close of ICSI procedure on screen in laboratory pan down to technician

ASSOCIATED PRESS
Oxford, UK - 30 September 2025
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16. SOUNDBITE (English) Professor Tim Child, Chair of HFEA's Scientific and Clinical Advances Advisory Committee (SCAAC)

ASSOCIATED PRESS
ARCHIVE London, UK – 17 August 2023

17. Various of embryologist at a London fertility clinic working in egg, sperm and embryo storage area
18. Various of embryologist opening and checking tank which stores embryos in liquid nitrogen
19. Embryologist pulls out cylinder which stores embryos
20. Embryologist holds tube with frozen embryos

ASSOCIATED PRESS
Oxford, UK - 30 September 2025
VIDEO CALL
ASSOCIATED PRESS
ARCHIVE London, UK – 17 August 2023

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