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Adult-Onset Still’s Disease: Clinical Insights on a Rare Autoinflammatory Disorder

In this in-depth medical video, Dr. Rezaian, a rheumatology specialist, walks you through Adult-Onset Still’s Disease (AOSD)—a rare but serious systemic autoinflammatory condition. Learn how to recognize the clinical triad of spiking fevers, arthralgia, and the characteristic salmon-colored rash, and understand the underlying cytokine storm involving IL-1, IL-6, and IL-18.

This video covers:
• Diagnostic criteria (including Yamaguchi’s Criteria)
• Key laboratory findings like hyperferritinemia
• Imaging features and differential diagnosis
• Current treatment strategies, including NSAIDs, corticosteroids, methotrexate, and IL-1/IL-6 inhibitors such as Anakinra, Canakinumab, and Tocilizumab
• Red flags for Macrophage Activation Syndrome (MAS) and how to monitor patients effectively

Ideal for medical students, residents, internists, rheumatologists, and healthcare professionals managing complex inflammatory conditions.

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Видео Adult-Onset Still’s Disease: Clinical Insights on a Rare Autoinflammatory Disorder канала TeachMeMedicine.org
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