Cell sorting for lymphoproliferative disorders in inborn immunity and cancers

Learn how cell sorting and flow cytometry are transforming the diagnosis and monitoring of immunological diseases.

In this webinar, Dr. Luis Allende (Hospital 12 de Octubre, Madrid) shares real-world applications of cell sorting in:

• Inborn errors of immunity (primary immunodeficiencies)
• Autoimmune lymphoproliferative syndrome (ALPS)
• TET2-related immune dysregulation
• Large granular lymphocyte (LGL) leukemia

Key insights:
- Identification of somatic vs germline mutations
- Functional validation of variants of unknown significance
- Tracking mutation burden across immune cell populations
- Personalized treatment monitoring using molecular markers

Technical highlights:
- Flow cytometry-based immunophenotyping
- Sorting of CD4, CD8, NK, and DNT cells
- Use of NGS and functional assays (apoptosis, methylation)

#CellSorting #FlowCytometry #Immunology #LGLLeukemia #PrimaryImmunodeficiency #BeckmanCoulter

Видео Cell sorting for lymphoproliferative disorders in inborn immunity and cancers канала Beckman Coulter Life Sciences