Risk and Benefits of Pfizer Vaccine in Adolescents | Absolute Risk Reduction | Parents Must Know

#RiskandBenefits #VaccineinAdolescent #AbsoluteRiskReduction

Hi everyone, welcome back this week. This week let's look at what we know about COVID in adolescents and how much risk and benefits are there to vaccinate adolescents. I will also walk you through the absolute risk reduction and number needed to treat calculation based on the Pfizer Phase III Trial result in adolescents.

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Disclaimer:

This video is Dr. Hong’s interpretation and summary of publically available scientific information
This video is not intended to serve as any advice regarding the treatment, prevention, and diagnosis of any diseases
Dr. Hong has no connections and receives no monetary compensation from any pharmaceutical companies and government.
This video is for educational purposes only.

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To learn more:
Physiology Short and Brief (1-min): Overview of Myocarditis
https://youtu.be/BCWctv7UxC4

Immunology Short and Brief Series:
https://youtube.com/playlist?list=PLk0eVd-2hM7ki8RUeYYOuuwUn6sBHLa2H

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Source References:

Hospitalization of adolescents aged 12-17 with laboratory-confirmed covid-19
https://www.cdc.gov/mmwr/volumes/70/wr/mm7023e1.htm

American Academy of Pediatrics
https://services.aap.org/en/pages/2019-novel-coronavirus-covid-19-infections/children-and-covid-19-state-level-data-report/

Laboratory confirmed COVID-19 associated hospitalizations
https://gis.cdc.gov/grasp/covidnet/COVID19_5.html

The total hospitalization rate during the third wave dominated by the Alpha variant was 2.1 per 100,000 in ages 12 to 17.
https://gis.cdc.gov/grasp/COVIDNet/COVID19_3.html

FDA
https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-authorizes-pfizer-biontech-covid-19-vaccine-emergency-use

CDC, v-safe
https://www.cdc.gov/coronavirus/2019-ncov/vaccines/safety/vsafe.html

COVID-19 Vaccine Safety in Adolescents Aged 12-17 years US, December 14, 2020, to July 16,2021
https://www.cdc.gov/mmwr/volumes/70/wr/mm7031e1.htm?s_cid=mm7031e1_w

VAERS
https://vaers.hhs.gov/

ACIP Meetings
https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2021-06/03-COVID-Shimabukuro-508.pdf

https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2021-06/05-COVID-Wallace-508.pdf

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