Gene Set Enrichment Analysis (GSEA) – simply explained!

What is GSEA and why is it one of the most popular pathway enrichment analysis methods? In this video, I will give you an overview of Gene Set Enrichment Analysis and how to use it to summarise your differential gene expression results.
We will go through the main concepts of GSEA to get a feeling of how it works and the differences with Over-Representation Analysis methods (ORA).
Hope you like it!

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Other interesting resources for GSEA:
Main GSEA webpage: https://www.gsea-msigdb.org/gsea/index.jsp
More on the method itself: https://www.pnas.org/doi/10.1073/pnas.0506580102
Paper comparing pathway enrichment analysis methods: https://genomebiology.biomedcentral.com/articles/10.1186/s13059-019-1790-4

Видео Gene Set Enrichment Analysis (GSEA) – simply explained! канала Biostatsquid