Systemic Lupus Erythematosus - I | Rheumatology Lectures | Medical Education | V-Learning

sqadia.com offers Rheumatology lectures online. This lecture focuses on the explanation of Systemic Lupus Erythematosus (SLE). This lecture explains the SLE pathogenesis and lupus nephritis pathology along with the clinical manifestations of Systemic Lupus Erythematosus.

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Lecture Duration - 01:10:16
Release Date - January 2020

Rheumatology Medicine Lectures Collection -
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Systemic lupus erythematosus (SLE) is an autoimmune disease in which organs and cells undergo damage initially mediated by tissue-binding autoantibodies and immune complexes. Systemic lupus erythematosus (SLE), also known simply as lupus, is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. Symptoms vary between people and may be mild to severe. In most patients, autoantibodies are present, or a few years be ore the first clinical symptom appears.

The proposed pathogenic mechanisms of SLE are illustrated in the second slide. SLE Pathogenesis are explained well. Interactions between susceptibility genes and environmental actors result in abnormal immune responses, which vary between different patients. After that Immunopagenesis is explained in detail.

In SLE, biopsies of affected skin show deposition o Ig at the dermal-epidermal junction (DEJ), injury to basal keratinocytes, and inflammation dominated by lymphocytes in the DEJ and around blood vessels and dermal appendages. Clinically unaffected skin may also show Ig deposition at the DEJ. In Lupus nephritis pathology skin biopsy and Renal biopsy are intensively touched.

International Society of Nephrology & Renal Pathology Society says that there are six classifications of Lupus Nephritis, it led towards the explanation of Pathology of Lupus. In Systemic lupus erythematosus guidelines of clinical features are well discussed here too.

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Musculoskeletal Manifestations, Cutaneous Manifestations, Renal Manifestations and nervous system manifestations are explained in detail in the explanation of systemic lupus erythematosus risk factor. Furthermore, vascular occlusions, pulmonary manifestations and cardiac manifestations along with Hematological Manifestations and Gastrointestinal Manifestations are thoroughly explained.

This is the first rheumatology lecture of Dr. Imran Ali on Systemic lupus erythematosus (SLE). In the second lecture on Systemic lupus erythematosus, He will explain the systemic lupus erythematosus differential diagnosis and management. These lectures of Dr. Ali Imran will help medical student to solve systemic lupus erythematosus case study easily.

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