Amiodarone Nursing Considerations, Side Effects and Mechanism of Action Pharmacology for Nurses

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Amiodarone

Generic Name: Amiodarone

Trade Name: Cordarone Indication a-fib, ventricular arrhythmias, SVT, ACLS protocol for v-fib and v-tach

Action: prolongs phase 3 of the action potential, makes the heart more tolerant to arrythmias, inhibits adrenergic stimulation, slows rate, decreases peripheral vascular resistance causing vasodilation

Therapeutic Class: antiarrhythmic class III, potassium channel blocker

Pharmacologic Class: none Nursing Considerations
 may lead to ARDS, pulmonary toxicity, CHF, bradycardia, hypotension
 increases risk for QT prolongation
 increases digoxin levels
 increases activity of warfarin
 monitor EKG continuously while on therapy
 assess for signs and symptoms of ARDS
 monitor liver function test
 check dosage with another RN
 teach pt to monitor pulse daily and report abnormalities
 avoid drinking grapefruit juice

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