BILIARY ATRESIA, Causes, Signs and Symptoms, Diagnosis and Treatment.
Biliary atresia, also known as extrahepatic ductopenia and progressive obliterative cholangiopathy, is a childhood disease of the liver in which one or more bile ducts are abnormally narrow, blocked, or absent. It can be congenital or acquired. It has an incidence of one in 10,000–15,000 live births in the United States,[2] and a prevalence of one in 16,700 in the British Isles.[3][4] Biliary atresia is most common in East Asia, with a frequency of one in 5,000.
The cause of biliary atresia in Egyptian infants has been proven to be as a result of aflatoxin induced cholangiopathy acquired prenatally in infants who have glutathione S transferase M1 deficiency.[5] Syndromic biliary atresia (e.g. Biliary Atresia Splenic Malformation (BASM)) has been associated with certain genes (e.g. Polycystic Kidney Disease) , and some infants with isolated biliary atresia may arise as a result of an autoimmune inflammatory response, possibly due to a viral infection of the liver soon after birth.[7] The only effective treatments [8] are operations such as the Kasai procedure and liver transplantation.[9]
Видео BILIARY ATRESIA, Causes, Signs and Symptoms, Diagnosis and Treatment. канала Medical Centric
The cause of biliary atresia in Egyptian infants has been proven to be as a result of aflatoxin induced cholangiopathy acquired prenatally in infants who have glutathione S transferase M1 deficiency.[5] Syndromic biliary atresia (e.g. Biliary Atresia Splenic Malformation (BASM)) has been associated with certain genes (e.g. Polycystic Kidney Disease) , and some infants with isolated biliary atresia may arise as a result of an autoimmune inflammatory response, possibly due to a viral infection of the liver soon after birth.[7] The only effective treatments [8] are operations such as the Kasai procedure and liver transplantation.[9]
Видео BILIARY ATRESIA, Causes, Signs and Symptoms, Diagnosis and Treatment. канала Medical Centric
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