Genome Nuts and Bolts

As a very general rule, there are three types of information that are encoded in genomes. Probably the one that most people are familiar with are genes that encode proteins. But, in the human genome, this represents only 5%, or even a little less of the entire genome.
There are also regions, and nobody really knows at present exactly where they all are and how big they are. But we know very well they exist and we've identified many of them that control when genes are turned on or off and how much. These are so-called regulatory regions. There are 2 different parts of the regulator regions. There are promoters that are located just before a particular gene that regulate gene transcription, and there are other more mysterious parts that are called enhancers, located far away from the gene in question. It turns out that the enhancers, which we think of as being very far away from the gene in question, actually may not be so far away. That's because up to now, we've been studying DNA and genomics in two dimensions. But life is in three dimensions.

Видео Genome Nuts and Bolts канала Precision Health